In the pharmaceutical industry, the guidelines set by the International Conference on Harmonization (ICH), and by United States Pharmacopeia (USP) and European Pharmacopeia (EP), mandate that manufacturing solvents have to be regulated due to their toxic and/or environmentally hazardous nature.

The USP General Chapter <467> Residual Solvents is a method widely used for identifying and quantifying residual solvents when there is no information available on what solvents are likely to be present. Our products are manufactured and verified by our QC department to validate the Certificate of Analysis which accompanies each product. Spex CertiPrep® offers analytes in dimethyl sulfoxide for Class 1, Class 2 and Class 3 solvents.

Can’t find the standards you are looking for? Spex CertiPrep® can make custom standards to meet your exact needs. Contact us for more information at [email protected] or call us at 732-549-7144.

Chemicals sold by Cole-Parmer are not intended for and should not be (i) used for medical, surgical or other patient oriented applications, or (ii) combined with any food product or ingested in any form.

This multi-component standard contains 15 components.

• 15 Organic Volatile Impurities, Class 2 Solvents, USP 467 Pharmaceutical Residual Solvent Standard is a 1 mL ampule which contains 19,400 μg/mL (19,400 ppm) Cyclohexane; 15,000 μg/mL (15,000 ppm) Methanol; 6,510 μg/mL (6,510 ppm) m-Xylene; 5,900 μg/mL (5,900 ppm) Methylcyclohexane; 4,700 μg/mL (4,700 ppm) cis-1,2-Dichloroethene; 4,700 μg/mL (4,700 ppm) trans-1,2-Dichloroethene; 4,450 μg/mL (4,450 ppm) Toluene; 3,450 μg/mL (3,450 ppm) Tetrahydrofuran; 3,000 μg/mL (3,000 ppm) Methylene chloride; 2,050 μg/mL (2,050 ppm) Acetonitrile; 1,900 μg/mL (1,900 ppm) 1,4-Dioxane; 1,840 μg/mL (1,840 ppm) Ethylbenzene; 1,800 μg/mL (1,800 ppm) Chlorobenzene; 1,520 μg/mL (1,520 ppm) p-Xylene; and 980 μg/mL (980 ppm) o-Xylene.

Hazardous material shipping fees may apply.