Recover clean extracts and shorten the time spent on method development using TELOS neo polymeric SPE columns. High surface area and capacity allow the use of smaller sorbent masses, leading to reduced elution volumes and evaporation/reconstitution steps. Polymeric sorbents are water-wettable and not affected by drying out, providing better flow characteristics, retention, and elution. Columns provide high and reproducible recoveries for a wide range of analytes, including acidic, neutral, basic, and multi-charged analytes.