The C18 columns provide hydrophobic retention with good peak shapes for neutral, acidic, and basic analytes. Based on ultrapure silica, the C18 performs well in a wide range of pH. The high surface area and the ligand bonding capability provide high retention of analytes, leading to more organic modifier that can be used to elute and greater MS sensitivity, shorter dry time in fraction collection, and more chance of resolution.

Columns come in 316L stainless steel (SS) tubing hardware. A SS female end fitting with a SS and PEEK frit system keeps the stationary phase in place and packed bed from disturbance. The SS end fitting accepts a male 10-32 threaded nut with standard 1/16" OD tubing.

Use the guard cartridges to maintain chromatographic integrity. They ensure erroneous materials are kept out of the more important and expensive analytical columns, leading to more accurate results. Simply match the sizes to select the correct guard cartridge for your column; guard cartridge holder 16470-89 is required to use the guard cartridges. In-line filters are available for your UPHLC and HPLC columns—order separately.